Poisoned Blade
- Effect Damage
- Poison
- Inheritance Reaction
- Control
C TierBossing · Mid
Overview
Overview
Half of every cut turns into poison; the inherited Catalyst makes two different afflictions explode together.
Good for: Late campaign, Reverberated and Echoes T1–T9: poison that works while you keep moving.
Strengths
- Damage that keeps going after the hit
- Area reaction with no need for the post-campaign (it's an Inheritance)
- Good against bosses
Weaknesses
- Slow clear (the poison takes time)
- Needs the Alchemist's Inheritance
- Still fragile
Loadout
What the build carries
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- Inheritance
- CatalystWandering Alchemist
Relics8
Core
- Rotten Earth
- Thorn Censer
- Deep Flask
Recommended
- Dirty Cloth
- Fine Nose
- Slow Drop
Optional
- Loose Step
- Open Spore
Progression
Progression trees
Explore the progression trees used in this build. Lit nodes are the ones it takes; the rest of each tree stays dimmed behind them.
Iris Fragments: 691
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Body
- Hardened Bark6/8+60% health (max +80%)
- Restoring Sap1/5+8% healing received
- Extra Flasks1/3+1 flask(s)
Power
- Sharp Gaze6/8+36% damage (max +48%)
- Steady Rhythm3/5+21% on basic attacks
Focus
- Reservoir3/5+30% maximum resource
- Serene Flow3/566% of natural flow
- Lasting Mark4/4+48% effect duration
Fortune
- Hole in the Pocket, Reversed1/5+12% gold
- Deep Pocket3/4+3 relic slot
Constellation Point: 16
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Affliction
- Cold Blood+22% Affliction Damage · +16% Affliction Duration
- Dirty Hand+1 Stacks
- +7% Affliction Damage ×3 · +8% Affliction Duration · +6% Affliction Chance · +6% Affliction Rate
Damage
- +6% Damage · +8% Damage with Basic Attacks · +8% Damage with Skills
RELIC SLOTS: +1
In practice
How to play
Open with Unstable Dose while invisible.
Keep every enemy poisoned.
Against packs, one cut on each, then back off.
Against bosses, nonstop combo at its back.
Careful: clear is slower than most mid builds.
To keep
The build card
The whole build in one image: ratings, loadout, trees and how to play.
Open the cardMeasured on Sep 28, 2026 · game v1.0.1 · test bench v8
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