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Detonated Plague

  • Effect Damage
  • Poison
  • Detonation
  • Cross-Form Link

B TierBossing · Endgame

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Overview

Overview

Druid of the Open Root floods everything with poison — and every crit, through Rupture, casts the Alchemist's Volatile Mixture and detonates the stacked afflictions.

Good for: Echoes T12–T20: bosses and elites with lots of health.

Strengths

  • Area detonation against afflicted packs
  • Poison goes through resistance (penetration)
  • The Crown spreads poison on its own

Weaknesses

  • Gem from another Form
  • Needs crit for Rupture (~42%)
  • Average clear

Loadout

What the build carries

Hover or tap an icon to see what it does, in the game's own words.

Inheritance
  • Predator SeedDruid of the Blind Roots
Mastery
  • Druid of the Open RootLV 7 · 34 points
Iris Links
  • RuptureTrigger Gem
  • Volatile MixtureLinked

Relics12

Core

  • Rotten Earth
  • Deep Flask
  • Old Plague
  • Plague of the Veil

Optional

  • Relay
  • Deep Humus
  • Edge of the Gaze
  • Whetstone

Legendary

  • Pestilent Heartluxury pick, random drop
  • Crowned Venomluxury pick, random drop

Sets

Pestilent Crown

Deep poison and fast poison.

  • Plague Flask
  • Pestilent Ring

2 pieces: At maximum stacks, Poison spreads to whoever is nearby.

Time Lord

Cooldown and repetition.

  • Broken Hand
  • Empty Hourglass

2 pieces: Every now and then a skill skips its cooldown and repeats itself.

Progression

Progression trees

Explore the progression trees used in this build. Lit nodes are the ones it takes; the rest of each tree stays dimmed behind them.

Iris Fragments: 1,653

Hover or tap a lit node to see what it does.

Body

  • Hardened Bark8/8+80% health (max +80%)
  • Restoring Sap2/5+16% healing received

Power

  • Sharp Gaze8/8+48% damage (max +48%)
  • Steady Rhythm5/5+35% on basic attacks
  • Elite Hunter4/4+36% against elites
  • Crownbreaker4/4+36% against bosses

Focus

  • Reservoir5/5+50% maximum resource
  • Serene Flow5/5110% of natural flow
  • Lasting Mark4/4+48% effect duration
  • Measured Haste4/4-20% cooldown (max -20%)

Fortune

  • Hole in the Pocket, Reversed1/5+12% gold
  • Deep Pocket4/4+4 relic slot

In practice

How to play

  1. Open with Plant Thorn and go in slashing.

  2. Keep everything afflicted.

  3. Against packs, spread it and let it detonate.

  4. Against bosses, stack and detonate on a loop.

  5. Careful: the Mixture gem belongs to another Form and takes a while to drop.

To keep

The build card

The whole build in one image: ratings, loadout, trees and how to play.

Open the card

Measured on Sep 28, 2026 · game v1.0.1 · test bench v8

Build card for Detonated Plague (Druid of the Blind Roots)

Steam

The Only Eye: Arcane Legacy

Your next attempt starts on Steam.

Twenty Forms, six regions and a whole endgame waiting past the first ending.

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Out now on Steam for PC.